Tuesday, August 17, 2010

I have few questions regarding genetic problems. so would you please like to help me?

in man keratosis is due to a dominant gene.( so it means a man with keratosis has two big SS and normal person has two small ss). and my teacher told me that males are not carrier so what when we get a Ss for males then are not they carriers.





2. ok this is easy that recessive genes are always small like ss, pp, or mm. but how do we know if dominant gene are homozygous or heterozygous when they didn't tell us?


and if you know this stuff can you give me your email so i can get help please


thank you

I have few questions regarding genetic problems. so would you please like to help me?
By the way, the way you have it described above, in a disease where the mutation causing the disease is dominant, there will be no carriers simply because if you have the gene, you have the disease, even if you have a wild type copy of the gene. The wild type copy can't do anything because the disease gene is dominant. so Ss is not a carrier because the definition of carriers is that they have a copy of the mutated gene but don't show the disease, and the Ss that you describe would have the disease.





As for the genetic nomenclature, it's a bit confusing. There is the wild type gene (we'll use your example and call it S), and there is a mutant gene. By convention, you usually call the mutant gene s. In general, the mutations have also been recessive or penetrant. The confusion comes in when you are talking about a dominant mutation. Does this get a capital or a small letter? What geneticists have taken to doing is to define the mutation and wild type alleles by something other than capital or small letters. S(wt) and S(kt) would describe the wild type and keratosis versions of the gene. The letters in parentheses are usually written as subscripts.





So to answer your question, that is the reason genetics came about as a discipline. To be able to look at an organism's traits and design tests to be able to tell whether it is homozygous or heterozygous. Just by looking at the phenotype (the outward expression of the genotype) you can't tell what the genotype is. You can do genetic crosses (in the case of animals) or look at the family history of the presence of the genes (for humans) to be able to tell whether it is homo- or heterozygous in any particular individual.





As far as email goes, you can contact us right here through the email button. This allows you to contact us without us having to give our email address out the public where we could get spammed in protest for ideas we present here.
Reply:A dominant feature means whether u get a Ss or SS the disease is going to express.%26amp; a carrier means that it has a potential allele but is able to express, it implies that Ss will be having this disease %26amp; SS will also be having this disease.So no question of male being a carrier.


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