Actinic means changes caused by radiation. Keratosis means a disorder relating to keratin, a fibrous structural protein that is very hard by nature.
Thus, actinic keratosis means a disease of keratin caused by radiation, in most cases solar radiation. It's a pre-cancerous malformation of the skin.
Here's how it works: the epidermis is made up of three primary structural proteins, collagen, elastin, and keratin. In general terms, collagen makes it soft and waterproof, elastin makes it stretchy, and keratin composes the very outermost layers to protect the softer parts from damage. Since keratin is such a naturally hard material, it makes up a much smaller portion of the normal ratio.
Calluses on hands or feet are the body's reaction to repeated minor abrasion. It ups the ratio of keratin in order to harden the skin and keep it from tearing.
In actinic keratosis, damage from a radiant energy source (like the sun) destroys and damages the epidermal cells repeatedly over a period of time, resulting in the body upping the keratin level to harden the skin up, resulting in the ugly bumps and patches.
Think of it like a callus, except instead of chafing making the skin toughen up, it's damage from the sun.
-Dr. Finn
What does actinic keratoses do on a cellular level to the actinic lesions?
Basically the cells become infected as a result of Ultra-Violent light (due to sensitivity, long-term sun exposure etc.) If its not treated properly, in can turn into an invasive squamous cell carcinoma.
This is mostly found in people with lighter skin although it CAN affect others as well. Good luck.
night blooming cereus
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