Saturday, July 24, 2010

What is keratoses?

Keratosis pilaris (KP) is a very common genetic follicular disease that is manifested by the appearance of rough bumps on the skin and hence colloqually referred to as "chicken skin". Primarily, it appears on the back and outer sides of the upper arms, but can also occur on thighs and buttocks or any body part except glabrous skin (like the palms or soles of feet). Worldwide, KP affects an estimated 40 to 50% of the adult population and approximately 50 to 80% of all adolescents. It is more common in women than in men. Varying in degree, cases of KP can range from minimal to severe.





There are several different types of keratosis pilaris, including keratosis pilaris rubra (red, inflamed bumps), alba (rough, bumpy skin with no irritation), rubra faceii (reddish rash on the cheeks) and related disorders.





Most people with keratosis pilaris do not know they carry it. While KP resembles goose bumps, it is characterized by the appearance of small rough bumps on the skin. As a result, it is often confused with acne.





Keratosis pilaris tends to occur as excess keratin, a natural protein in the skin, accumulates around hair follicles (process known as hyperkeratinization). Unattractive more than anything else, it most often appears as a proliferation of tiny hard bumps that are seldom sore or itchy. Though people with keratosis pilaris experience this condition year round, it’s during the colder months when moisture levels in the air are lower that the problem can become exacerbated and the “goose bumps” are apt to look and feel more pronounced in color and texture.





Although exfoliation, intensive moisturizing cremes, and medicated lotions containing alpha-hydroxy acids or urea may improve the appearance and texture of affected skin, results are not permanent. There is no known cure for this condition





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Seborrheic keratosis (Seborrhoeic keratosis) a kind of benign skin growth that is very common among people over 40 years of age. The growths resemble flattened or raised warts, but have no viral origins and may exhibit a variety of colors, from pink or yellow through brown and black. Because only the top layers of the epidermis are involved, seborrheic keratoses are often described as having a "pasted-on" appearance.





Because the tumors are rarely painful, treatment is not often necessary. There is a small risk of localized infection caused by picking at the lesion. If a growth becomes excessively itchy, or if it is irritated by clothing or jewelry, cryosurgery has been found to be highly effective in their removal. The main danger associated with seborrheic keratoses lies in their resemblance to malignant melanomas, which has sometimes led to a misdiagnosis of the cancerous lesions. If there is any doubt, a skin biopsy will allow a physician to make a correct diagnosis. A mutation of a gene codigng for a growth factor receptor (FGFR3), has been found in 40% of seborrheic keratosis.

What is keratoses?
growth of hard hornlike tissue on the skin


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